2. Signaling Pathways
  3. Anti-infection
  4. Parasite

Parasite

Parasite

Related Products

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Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Parasite Isoform Specific Products:

Parasite Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-12643R
    Eprinomectin (Standard)
    		Inhibitor
    Eprinomectin (Standard) is the analytical standard of Eprinomectin. This product is intended for research and analytical applications. Eprinomectin is a type of avermectin. Eprinomectin, as a broad-spectrum fungicide, has insecticidal, insecticidal and acaricidal activities. Eprinomectin induces apoptosis and autophagy in prostate cancer cells and has antitumor activity.
    Eprinomectin (Standard)
  • HY-118865
    Piperaquine tetraphosphate
    		Inhibitor
    Piperaquine tetraphosphate is a potent antimalaria agent. Piperaquine tetraphosphate shows inhibition for chloroquine-sensitive and the chloroquine-resistant isolates. Piperaquine tetraphosphate in combination with dihydroartemisinin has the potential for the research of chloroquine-resistant malaria.
    Piperaquine tetraphosphate
  • HY-P5694
    Human α-defensin 5
    		Inhibitor
    Human α-defensin 5 is an antiviral peptide. Human α-defensin 5 blocks infection of non-enveloped viruses, including AdV, HPV, and polyomaviruses (IC50: 0.6-1.25 μM for HPV16). Human α-defensin 5 can bind to the viral capsid and blocks escape of the virus from the endosome. Human α-defensin 5 increases HIV binding to the cell surface. Human α-defensin 5 also has parasiticidal activity.
    Human α-defensin 5
  • HY-B2015S
    Carbosulfan-d18
    		Inhibitor
    Carbosulfan-d18 is the deuterium labeled Carbosulfan. Carbosulfan inhibited relatively potently CYP3A4 and moderately CYP1A1/2 and CYP2C19 in pooled HLM (human livers). Carbosulfan activation is predominantly catalyzed in humans by CYP3A4.
    Carbosulfan-d<sub>18</sub>
  • HY-147933
    Antitrypanosomal agent 8
    		Inhibitor
    Antitrypanosomal agent 8 (compound 3b) has potent antitrypanosomal activity against Trypanosoma brucei with an IC50 value of 0.79 μM and exhibits certain cytotoxicity in L6 cells (IC50=80.95 μM).
    Antitrypanosomal agent 8
  • HY-149939
    Antimalarial agent 26
    		Inhibitor
    Antimalarial agent 26 is an orally active 1,4-naphthoquinones derivative with antimalarial activities. Antimalarial agent 26 shows cytotoxicity against P. falciparum and selectivity over mammalian cell lines. Antimalarial agent 26 inhibits P. burghei induced parasitemia in vivo.
    Antimalarial agent 26
  • HY-N1480S1
    (-)-Fucose-13C-1
    (-)-Fucose-13C-1 is the 13C labeled (-)-Fucose. (-)-Fucose is classified as a member of the hexoses, plays a role in A and B blood group antigen substructure determination, selectin-mediated leukocyte-endothelial adhesion, and host-microbe interacti[
    (-)-Fucose-<sup>13</sup>C-1
  • HY-B0978S
    Diethyltoluamide-d10
    Diethyltoluamide-d10 is the deuterium labeled Diethyltoluamide. Diethyltoluamide is the most common active ingredient in insect repellents. It is intended to provide protection against mosquitoes, ticks, fleas, chiggers, leeches, and many other biting insects.
    Diethyltoluamide-d<sub>10</sub>
  • HY-155301
    Antileishmanial agent-24
    		Inhibitor
    Antileishmanial agent-24 (compound 33) is an antileishmanial agent with an IC50 of 5.39 μM against amastigote.
    Antileishmanial agent-24
  • HY-146044
    Antiparasitic agent-6
    		Inhibitor
    Antiparasitic agent-6 (compound 5b) has selectively antiparasitic activity against Leishmania infantum (L. infantum) with an IC50 value of 3.89 μM. Antiparasitic agent-6 also has certain cytotoxicity against HepG2 (CC50 = 13.64 μM).
    Antiparasitic agent-6
  • HY-119688
    Amabiline
    		Inhibitor
    Amabiline is a compound isolated from a plant that contains a variety of bioactive ingredients including Amabiline. The plant as a whole has a variety of traditional uses and also has certain pharmacological activity and toxicity.
    Amabiline
  • HY-144294
    Purine phosphoribosyltransferase-IN-1
    		Inhibitor
    Purine phosphoribosyltransferase-IN-1 (Compound (S,R)-48) is a potent inhibitor of the Plasmodium falciparum (Pf), P. vivax (Pv) and Trypanosoma brucei (Tbr) 6-oxopurine purine phosphoribosyltransferases (PRTs), with Ki values of 50, 20, and 2 nM, respectively.
    Purine phosphoribosyltransferase-IN-1
  • HY-158776
    SLU-10482
    		Inhibitor
    SLU-10482 is an orally active anti-parasitic agent, that inhibits Cryptosporidium parvum with an IC50 of 0.0687 μM. SLU-10482 exhibits anti-infective efficacy in C. parvum infected mice with an AC50 of 0.0686 μM.
    SLU-10482
  • HY-168862
    Insecticidal agent 18
    		Inhibitor
    Insecticidal agent 18 (compound 34) is a potent insecticidal agent. Insecticidal agent 18 shows acaricidal activity.
    Insecticidal agent 18
  • HY-145287
    S-MGB-234
    S-MGB-234 is a minor groove binder of Animal African Trypanosomiasis (AAT). S-MGB-234 displays excellent in vitro activities against the principal causative organisms of AAT; Trypanosoma congolense, and Trypanosoma vivax. S-MGB-234 does not show cross-resistance with the current diamidine agents and are not internalized via the transporters used by diamidines.
    S-MGB-234
  • HY-101660
    Nifursemizone
    		Inhibitor 99.25%
    Nifursemizone is an antiprotozoal agent.
    Nifursemizone
  • HY-146487
    Anti-infective agent 1
    		Inhibitor
    Anti-infective agent 1 (compound 3a) is a potent and selective antiprotozoal and antimycobacterial agent. Anti-infective agent 1 shows antiparasitic activity against P. falciparum and T. brucei rhodesiense, with IC50 values of 10.95 and 0.06 μM, respectively. Anti-infective agent 1 shows antimycobacterial activity against Mycobacterium smegmatis with a MIC of 8 μg/mL.
    Anti-infective agent 1
  • HY-168656
    Ac-Atovaquone
    		Inhibitor
    Ac-Atovaquone is a potent cytochrome bc1 inhibitor and also is an ester-linked acetyl derivative of atovaquone (HY-13832). Ac-Atovaquone has the potential for the research of malaria.
    Ac-Atovaquone
  • HY-163484
    ELQ-650
    		Inhibitor
    ELQ-650 is a quinolone derivative, that exhibits antimicrobial activity against several protozoan parasites, including the intraerythrocytic parasites Plasmodium and Babesia. ELQ-650 attenuates babesiosis in immunosuppressed mice.
    ELQ-650
  • HY-168619
    DNA crosslinker 6
    		Inhibitor
    DNA crosslinker 6 (compound 1) is an anti-kinetoplastid compound. DNA crosslinker 6 has a strong ability to bind AT-DNA and can inhibit the binding of AT-hook 1 to DNA (IC50=0.03 µM). In addition, DNA crosslinker 6 also has antiprotozoal activity, with an EC50 value of 0.83 µM for the inhibition of T. brucei.
    DNA crosslinker 6
Parasite Isoform Comparison

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